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Obesity pandemics is a huge problem for modern society, overall quality of life and longevity. Despite common option and theory that count calories in/calories out, often problems and equation are not so simple, for many members of worldwide population.

Weight is the result of human body’s fight against Earth’s gravity. It is sometimes used as a measurable parameter in some studies as it is cheap to measure the weight of many people. Fat and obese people do not want only to lose weight, they want to lose fat on first place. Weight is irrelevant, unless you are not professional athlete, with scale demands or performance aspects.

Weight is pretty „ungrateful“ term to connect with, mostly connected to food consumption and calorie intake, would suggest rather connecting to terms like:

Key words and terms: triglycerides, glucose metabolism, blood pressure, hypertension, glucose control, reduced appetite and food intake, satiety, inappropriate eating patterns, binge eating, liver fat buildup, decreasing cardiovascular risk factors in obese people, fighting inflammation.

Ingredients and performance aspects analysis

  1. Spirulina

Spirulina is a non-toxic blue-green algae. It is a source of phycocyanobilin. Preliminary evidence suggests spirulina is remarkably potent at protecting the brain and reducing liver fat. Spirulina is a blue-green algae. It is an easily produced, non-toxic species of Arthrospira bacteria. Spirulina is often used as a vegan source of protein and vitamin B12. It is between 55-70% protein, but studies suggest it is a subpar source of B12, as the vitamin is not absorbed well after ingestion.

Human evidence suggests that spirulina can improve lipid and glucose metabolism, while also reducing liver fat and protecting the heart. Animal studies are very promising as well, as spirulina has been shown to be of similar potency as commonly used reference drugs, when it comes to neurological disorders. These effects also extend to arthritis and immunology.

Related scientific studies

Triglycerides – In populations with metabolic syndrome or related morbidities (diabetes, hyperlipidemia, hypertension, etc.) spirulina in a variety of doses between 1-8g daily is able to reduce triglycerides up to 10-15%.

Blood glucose – Reductions in blood glucose seen are not overly remarkable or noteworthy

HbA1c – HbA1c (Glycated hemoglobin) is a biomarker of glucose metabolism, and higher HbA1c is associated with more disease progression and comorbidities in states of insulin resistance or diabetes. Lone study noted a decrease from 9% to 8% with 2g spirulina, which is somewhat notable but requires more evidence to establish this.

Weight – Currently not enough evidence to support any significant interaction with weight

Chlorella is a freshwater algae that is commonly supplemented by vegan populations (similar to Spirulina). Chlorella appears to be a bioavailable source of both Iron and Vitamin B12, and may have other benefits.

Related scientific studies

Blood pressure – Might reduce blood pressure in some instances but does not appear remarkably potent.

Weight – No significant effects on body weight

  • Chromium picolinate

Chromium is an essential mineral. It regulates glucose metabolism and insulin sensitivity. Supplementing more chromium than the body needs does not produce reliable results, but it may be associated with minor benefits to diabetics. It is found in trace amounts in plant products, specifically grains.

Chromium regulates insulin in the body. It is sometimes supplemented to improve insulin action in the body. When chromium is supplemented by people with normal or elevated chromium levels, no reliable effect is achieved. People with a subclinical chromium deficiency (below optimal, but not a true deficiency) may experience benefits when supplementing chromium, but more research is required to confirm this effect.

Chromium’s main mechanism is directly tied to chromodulin. Chromodulin, a protein, normally augments the signaling of insulin receptors. If this protein is impaired, insulin’s ability to work in the body is greatly reduced.

Related scientific findings

Blood glucose – In looking at the entirety of the data on type II diabetic persons, there does appear to be a mild reduction in fasting blood glucose despite no apparent changes in insulin sensitivity or HbA1c. No significant or reliable effect in non-diabetic persons.

Weight – There is no significant influence of chromium on weight in either healthy persons or those with diabetes, and although a possible interaction may occur in some instances of better glucose control or reduced appetite they are not frequent enough to establish a solid relationship to chromium.

Appetite – There may be a role in reducing appetite specifically in persons who self-report inappropriate eating patterns and carbohydrate cravings, with no known effect in persons who do not report such.

Food intake – No significant influence on food intake in standard diabetics, although limited evidence suggest a possible role specifically in persons who self-report elevated carbohydrate cravings and inappropriate eating patterns due to urges.

Binge eating – Although chromium showed an ability to reduce binge eating symptoms in persons with the disorder, this failed to reach statistical significance.

  • Blueberry

Blueberries are a fruit that contain a lot of molecules called anthocyanins. These antioxidant compounds are often supplemented for their ability to improve cognition.

Blueberries are a small, blue-purple fruit that belong to the genus vaccinium, which also includes cranberries and bilberries. Blueberries are a popular food and frequently supplemented. The antioxidant and anthocyanin content of blueberries makes them particularly effective at reducing cognitive decline, supporting cardiovascular health, protecting the liver, and reducing liver fat buildup.

Blueberries may also have a potential nootropic effect. They have been found to improve cognition in people undergoing cognitive decline, but there is also some rodent evidence that suggests blueberries can improve cognition in healthy young people as well. They may also have a role to play in promoting the growth of nervous tissue and reducing neurological inflammation. Blueberries can be eaten or supplemented through blueberry powder. Blueberries are both a food product and dietary supplement.

Related scientific findings

Blood pressure – A decrease in blood pressure has been noted in persons at risk for cardiovascular disease (6% systolic and 4% diastolic), but this may be limited to high risk individuals only.

Oxidation of LDL – There appears to be a reduction in LDL oxidation, with the one chronic study suggesting a 27% reduction (the acute study noting less of a protective effect).

Appetite – No significant influence on appetite or satiety

  • Capsaicin

The exact molecule found in hot peppers that burns your face off, acts via adrenaline receptors and TRPV1 (like Evodia) to increase heat quickly. Can burn body fat with minimal potency, fight inflammation with decent potency, and prevent cancer with indeterminate potency.

Related scientific findings

Blood glucose – A possible reduction in blood glucose may occur secondary to pancreatic stimulation with high doses of capsaicin


Most suitable product from B!TONIC line for positioning for diabetes, and link between diabetes and obesity is pretty strong. Obesity is believed to account for 80-85% of the risk of developing type 2 diabetes, while recent research suggests that obese people are up to 80 times more likely to develop type 2 diabetes than those with a BMI of less than 22. In general, being overweight or obese is having a body mass index – BMI – of 30 or greater.

Please find weight loss psychology, hormones and motivation case study in separate document, for weight loss it is definitely more important than this one, but there is some points that can be used for GREEN METABOLISM positioning for OBESITY and WEIGHT LOSS.

Sebastijan Orlić, PhD

Categories: General


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